Rates and Predictors of Seizure Freedom With Vagus Nerve Stimulation for Intractable Epilepsy

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Rates and Predictors of Seizure Freedom With Vagus Nerve Stimulation for Intractable Epilepsy

BACKGROUND Neuromodulation-based treatments have become increasingly important in epilepsy treatment. Most patients with epilepsy treated with neuromodulation do not achieve complete seizure freedom, and, therefore, previous studies of vagus nerve stimulation (VNS) therapy have focused instead on reduction of seizure frequency as a measure of treatment response. OBJECTIVE To elucidate rates a...

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Vagus nerve stimulation: predictors of seizure freedom.

OBJECTIVES To identify predictive factors for the seizure-free outcome of vagus nerve stimulation (VNS). METHODS All 47 patients who had undergone VNS implantation at one centre and had at least one year of follow up were studied. They underwent complete presurgical evaluation including detailed clinical history, magnetic resonance imaging, and long term video-EEG with ictal and interictal re...

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Long-term seizure and psychosocial outcomes of vagus nerve stimulation for intractable epilepsy

Vagus nerve stimulation (VNS) is a widely used adjunctive treatment option for intractable epilepsy. Most studies have demonstrated short-term seizure outcomes, usually for up to 5 years, and thus far, none have reported psychosocial outcomes in adults. We aimed to assess long-term seizure and psychosocial outcomes in patients with intractable epilepsy on VNS therapy for more than 15 years. We ...

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Vagus nerve stimulation: Outcome and predictors of seizure freedom in long-term follow-up

OBJECTIVES To present long-term outcome and to identify predictors of seizure freedom after vagus nerve stimulation (VNS). METHODS All patients who had undergone VNS implantation in the Epilepsy Centre Bethel were retrospectively reviewed. There were 144 patients who had undergone complete presurgical evaluation, including detailed clinical history, magnetic resonance imaging, and long-term v...

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Assessment of Vagus Nerve Stimulation for Epilepsy

Introduction and methodology. Despite a recent surge in availability of new antiepileptic medications and advances in surgical therapy for epilepsy, intractable epilepsy remains a very significant problem. At least 25 to 50% of patients with epilepsy suffer from breakthrough seizures or debilitating side effects of medications. We need a safe and effective treatment for these people, even if it...

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ژورنال

عنوان ژورنال: Neurosurgery

سال: 2015

ISSN: 0148-396X,1524-4040

DOI: 10.1227/neu.0000000000001165